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86-5918-43 anti- RBX1 antibody 100ug FNab07199 アズワン 正規保証

86-5918-43anti- RBX1 antibody 100ug FNab07199 正規保証

86-5918-43 一次抗体 抗体 試薬 上段は左右に全開するスライド式 konidelaproductioncompany.com chrysosplenium1u-kxpjowg9w 38000円 fd8HChLZmSkYMwb 86-5918-43anti- RBX1 antibody 100ug FNab07199 正規保証 86-5918-43 anti- RBX1 antibody 100ug FNab07199 アズワン 正規保証 FNab07199 100ug antibody RBX1 86-5918-43anti- アズワン FNab07199 100ug antibody RBX1 anti- 86-5918-43 一次抗体 抗体 試薬 上段は左右に全開するスライド式 konidelaproductioncompany.com chrysosplenium1u-kxpjowg9w 38000円 fd8HChLZmSkYMwb 86-5918-43anti- RBX1 antibody 100ug FNab07199 正規保証 86-5918-43 anti- RBX1 antibody 100ug FNab07199 アズワン 正規保証 FNab07199 100ug antibody RBX1 86-5918-43anti- アズワン FNab07199 100ug antibody RBX1 anti- 86-5918-43 一次抗体 抗体 試薬

試薬
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  • アズワン株式会社 輸入試薬グループ
  • TEL:06-6447-8641
  • FAX:06-6447-8642
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特徴

  • Background:E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair. The functional specificity of the E3 ubiquitin-protein ligase complexes depends on the variable substrate recognition components. As a component of the CSA complex promotes the ubiquitination of ERCC6 resulting in proteasomal degradation. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme, like CDC34, to the complex and brings it into close proximity to the substrate. Probably also stimulates CDC34 autoubiquitination. May be required for histone H3 and histone H4 ubiquitination in response to ultraviolet and for subsequent DNA repair. Promotes the neddylation of CUL1, CUL2, CUL4 and CUL4 via its interaction with UBE2M. Involved in the ubiquitination of KEAP1, ENC1 and KLHL41. In concert with ATF2 and CUL3, promotes degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM.

仕様

  • サイズ:100ug
  • Host:Rabbit
  • Specificity:Human, Mouse, Rat
  • Clonality:polyclonal
  • Application:ELISA, WB, IHC, IP
  • Isotype:IgG
  • Form:liquid
  • Purification:Immunogen affinity purified
  • Purity:≥95% as determined by SDS-PAGE
  • Immunogen:ring-box 1
  • Manual Links:https://static.fn-test.com/product/manuals/antibody/FNab07199.pdf
  • この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
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